Expansion Offering Enhances and Broadens Bausch + Lomb’s Surgical Portfolio with Unique and Clinically Proven Comprehensive Dye Platform

VAUGHAN, ON and CASORIA, Italy , Sept. 1, 2022 /PRNewswire/ — Bausch + Lomb Corporation (NYSE/TSX: BLCO) (“Bausch + Lomb”), a leading global eye health company dedicated to helping people see better to live better, plus Alfa Instruments s. r. l., an Italian ophthalmic medical device company, today announced that the companies have entered into an exclusive distribution agreement under which Bausch + Lomb will distribute and commercialize Alfa Instruments’ line of surgical intraocular dyes, Vitreocare, globally with the exception of Italia , where Alfa Instruments is based. The agreement expands and enhances Bausch + Lomb’s Surgical portfolio offering with Alfa Instruments’ differentiated intraocular dyes, which have been proven safe and effective in the European Union (EU).

“The addition of these clinically proven intraocular dyes to our already comprehensive surgical portfolio will help surgeons enhance the visibility of targeted eye tissues, as well as identify transparent layers of the eye during vitreoretinal, corneal in addition to cataract surgery, ” 1-6 said Joe Gordon , president, Global Consumer, Vision Care and Medical, Bausch & Lomb. “Our exclusive collaboration with Alfa Instruments demonstrates our commitment to providing vision care professionals with innovative products that are designed to help them achieve the best possible medical outcomes for their patients. ”

Under the particular agreement, Bausch + Lomb will assume responsibility for all submission and commercial activities of Vitreocare intraocular dyes, which includes:

  • Vitreo Lutein with regard to vitreous staining
  • Single Lutein Blue regarding internal limiting membrane (ILM) staining
  • Double Lutein Blue for ILM and epiretinal membrane (ERM) staining
  • Phaco Lutein intended for anterior capsule staining
  • Trypan Blue to get anterior capsule staining

The unique common thread of Vitreocare intraocular dyes is lutein, a natural blue light filter. Research has shown that lutein is a safe and effective dye agent, and its antioxidant properties can further protect the retina during attention surgery. 1-6 Moreover, Single Lutein Blue and even Double Lutein Blue are formulated with the new high purity (> 99%) molecule Pure Benzyl-Brilliant Blue (PBB®). PBB® has been specifically designed within order in order to improve ILM binding affinity and to avoid diffusion in to retinal layers, in order to avoid potential cytotoxicity on off-target tissues. 7  

“We  are usually honored together with delighted to be able to collaborate along with Bausch and up. Lomb,   one of the best known and most respected eye care companies inside the world, because it will expand access of our intraocular dyes through Bausch plus Lomb’s broad distribution network, ” stated Fabio David , CEO, Alfa Devices. “We look forward for you to working together to help improve the vision needs of patients undergoing vitreoretinal, cataract or corneal surgical treatment. ”

Alfa Instruments’ operative dyes are currently CE marked and sold in the EU, the United Kingdom , and additionally Switzerland . Bausch + Lomb expects to begin the supply from the intraocular dyes throughout all EUROPEAN UNION countries, except for Italy , during typically the first half of 2023. Bausch & Lomb not to mention Alfa Instruments are also in the process associated with exploring regulatory requirements and also approvals regarding the surgery dyes in other markets.

For more information on VitreoCare, visit www.vitreocare.com .

About Alfa Instruments

Founded in 2005 as a branch involving Alfa Intes, an italian pharmaceutical organization with more than sixty (60) years of experience in this pharmaceutical industry, Alfa Instruments manufactures, develops and markets specialized products for the precise and diagnostic ophthalmic sector. The company has more than 40 many years of experience in both sectors, and has grown exponentially around recent yrs by establishing itself as the market leader in high-tech diagnostic instruments. In 2020, with the aim of enlarging its manufacturing capabilities, the company opened a new manufacturing site in southern Italy , exclusively focused on the production of sterile injectables, including its full line connected with surgical chemical dyes. To find out more, visit www.alfaintes.it   as well as connect with us on LinkedIn   and Facebook .

About Bausch + Lomb

Bausch + Lomb is dedicated to protecting and enhancing the gift of sight for millions of people around often the world – from your moment with birth via every phase of life. Its extensive portfolio of more than 400 items includes contact lenses, lens care products, eye maintenance systems, ophthalmic pharmaceuticals, over-the-counter products and ophthalmic high tech devices and instruments. Started in 1853, Bausch and up. Lomb has a significant global research plus development, producing and commercial footprint using more than 12, 000 employees and a presence on nearly 100 countries. Bausch + Lomb is headquartered in Vaughan, Ontario together with corporate offices in Bridgewater, New Jersey . For more information, visit  www.bausch.com   in addition to interact with all of us on Twitter , LinkedIn , Fb and Instagram .

Forward-looking Statements

This news release may contain forward-looking statements, which may generally be identified by the exact use for the words “anticipates, ” “hopes, ” “expects, ” “intends, ” “plans, ” “should, ” “could, ” “would, ” “may, ” “believes, ” “estimates, ” “potential, ” “target, ” or even “continue” and even variations or perhaps similar expressions. These statements are based upon the current expectations together with beliefs about management and are subject to certain risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. These dangers and questions include, but are not limited to, the risks and uncertainties discussed in Bausch plus Lomb’s filings with the particular U. S. Securities and additionally Exchange Commission and the Canadian Securities Administrators, which factors are incorporated herein by reference. They also include, but are not limited in order to, risks not to mention uncertainties caused by or maybe relating to be able to the evolving COVID-19 pandemic, and the fear of that pandemic as well as potential effects, the severity, duration and also future impact of which are highly uncertain as well as cannot be predicted, and which usually may have a material adverse impact upon Bausch + Lomb, which includes but not restricted to its project development timelines, launches and costs (which might increase). Readers are cautioned not for you to place undue reliance about any of these forward-looking statements. These forward-looking claims speak only as of typically the date hereof. Bausch & Lomb undertakes no obligation to update some of these forward-looking statements to help reflect events or circumstances after the date of this news release or to reflect actual outcomes, unless required by law.  

References

  1. Lutein: A New Dye pertaining to Chromovitrectomy . Mauricio Maia et al. Retina, The particular Journal in Retinal and Vitreous Diseases, 34: 262–272, 2014.
  2. Phacodyne versus VisionBlue as vital dyes during Descemet membrane endothelial keratoplasty.   Bucher et al. Graefes Arch Clin Exp Ophthalmol 2015 Aug; 253(8): 1411-2.
  3. Muller cells activation and retinal damage after macular peeling: comparison between dyes. Romano et ing. American Academy of Ophthalmology (AAO) 2016 – PO 270.
  4. Macular peeling-induced retinal damage: clinical plus histopathological evaluation after using different inorganic dyes.   Romano ainsi que al. Graefe’s Archive meant for Clinical in addition to Experimental Ophthalmology (2018) 256: 1573– 1580.
  5. Use of Lutein and even Zeaxanthin Alone or Combined with Brilliant Glowing blue to Identify Intraocular Structures Intraoperatively. Sousa-Martins  et ‘s. Retina, Typically the Journal from Retinal together with Vitreous Illnesses, 2012 Jul; 32(7): 1328-36.
  6. Soluble Lutein inside Combination using BrilliantBblue as a New Dye designed for Chromovitrectomy. Badaro et approach. Graefes Arch Clin Exp Ophthalmol 2014 Jul; 252(7): 1071-8.
  7. New Brilliant Blue G Derivative because Pharmacological Tool in Retinal Surgery . Spadaro ou al. Front. Pharmacol. 2020 May; 11: 708.

PBB Pure Benzyl-Brilliant Blue is a trademarks of Alfa Instruments.
All other product/brand names are trademarks of this respective owners.  
© 2022 Bausch & Lomb Incorporated or the affiliates.

SOURCE Bausch + Lomb Corporation

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